Description

NVIDIA Clara Parabricks GPU-accelerated fast, accurate algorithm for mapping methylated DNA sequence reads to a reference genome, performing local alignment, and producing alignment for different parts of the query sequence

Input

name:type
description
pattern

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

reads

:file

fastq.gz files

*.fastq.gz

meta2

:map

Groovy Map containing fasta information

fasta

:file

reference fasta file - must be unzipped

*.fasta

meta3

:map

Groovy Map containing index information

index

:file

reference BWA index

*.{amb,ann,bwt,pac,sa}

known_sites

:file

(optional) known sites file(s) for calculating BQSR. markdups must be true to perform BQSR.

*.vcf.gz

Output

name:type
description
pattern

bam

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.bam

:file

Sorted BAM file

*.bam

bai

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.bai

:file

index corresponding to sorted BAM file

*.bai

qc_metrics

qc_metrics

:directory

(optional) optional directory of qc metrics

qc_metrics

bqsr_table

*.table

:file

(optional) table from base quality score recalibration calculation, to be used with parabricks/applybqsr

*.table

duplicate_metrics

duplicate-metrics.txt

:file

(optional) metrics calculated from marking duplicates in the bam file

*-duplicate-metrics.txt

versions_parabricks

${task.process}

:string

The process the versions were collected from

parabricks

:string

The tool name

pbrun version | grep -m1 '^pbrun:' | sed 's/^pbrun:[[:space:]]*//'

:string

The command used to generate the version of the tool

Topics

name:type
description
pattern

versions

${task.process}

:string

The process the versions were collected from

parabricks

:string

The tool name

pbrun version | grep -m1 '^pbrun:' | sed 's/^pbrun:[[:space:]]*//'

:string

The command used to generate the version of the tool

Tools

parabricks
custom

NVIDIA Clara Parabricks GPU-accelerated genomics tools